What Should I Know Before Getting a Disulfiram Implant?
Disulfiram (commonly known as Esperal) is a widely used support tool in the treatment of alcohol addiction. Administered in the form of an implant, it helps patients stay sober by causing an immediate and unpleasant physical reaction if alcohol is consumed. While effective, this method requires proper preparation, medical oversight, and a clear understanding of how it works. In this article, we explain what Disulfiram does, who it’s for, how the procedure is carried out, and what to expect before and after treatment.
How Does It Work?
The most important rule when using Disulfiram is simple: do not consume alcohol. This medication works by blocking the enzyme acetaldehyde dehydrogenase, which prevents the body from properly breaking down alcohol. As a result, drinking even small amounts of alcohol causes an almost immediate onset of severe hangover-like symptoms.
Within 5 to 10 minutes after drinking, you may experience skin flushing, rapid heartbeat, shortness of breath, nausea, vomiting, pounding headache, confusion, or even circulatory collapse. These symptoms can last from 30 minutes to several hours and may require urgent medical intervention.
If you consume alcohol while having a Disulfiram implant, seek emergency medical help immediately.
To ensure your safety, it is strongly recommended that you wear a medical alert bracelet or carry a card stating that you are using Disulfiram – so that any medical professional treating you is aware.
What Should I Know Before the Procedure?
Disulfiram can only be administered with the patient’s informed and written consent. Before the procedure, you will be fully informed of potential side effects. A valid photo ID is required to complete the consent process.
It is crucial that you do not consume alcohol for at least 24 to 48 hours before treatment.
Do Not Use Disulfiram If:
- You are allergic to Disulfiram
- You have recently taken metronidazole or paraldehyde
- You have used any products containing alcohol (e.g. mouthwash, cooking wine, cough syrup, vinegar, desserts with alcohol)
Contraindications include:
- Alcohol consumption within 24 hours of treatment
- Pregnancy or breastfeeding
- Use of phenytoin, tuberculosis medications, or blood thinners
- Heart failure or coronary artery disease
- History of heart attack or ischemia
- High blood pressure
- Inflammation of blood vessels
- Optic neuritis
- Psychosis or past suicide attempts
You should also inform your doctor if you:
- Have a personality disorder
- Have a history of brain injury, stroke, or epilepsy
- Suffer from hypothyroidism
- Have lung or liver disease
- Have a history of mental illness
What to Expect During the Procedure
The procedure is quick and performed under local anesthesia. A small incision is made in the buttocks area, and Disulfiram tablets are inserted deep into the muscle. The number of tablets is determined by body weight—typically one tablet per 10 kilograms.
The entire treatment takes around 15-20 minutes and is generally well tolerated.
Looking for Help?
If you’re considering Disulfiram therapy as part of your recovery, make sure you are guided by professionals. At our clinic in Dublin, you’ll find comprehensive information and support tailored to your needs.
Let us help you take the first step toward lasting sobriety.
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